Early reduced dopaminergic tone mediated by D3 receptor and dopamine transporter in absence epileptogenesis

Author:

Cavarec Fanny1,Krauss Philipp12,Witkowski Tiffany13,Broisat Alexis4,Ghezzi Catherine4,De Gois Stéphanie5,Giros Bruno56,Depaulis Antoine1,Deransart Colin1ORCID

Affiliation:

1. Grenoble Alpes University National Institute of Health and Medical Research U1216, Grenoble Alpes University Hospital Center Grenoble Institute of Neurosciences Grenoble France

2. Department of Neurosurgery Rechts der Isar Hospital Munich Germany

3. Clermont Auvergne University National Institute of Health and Medical Research U1240 Molecular Imaging and Theranostic Strategies Clermont‐Ferrand France

4. National Institute of Health and Medical Research Mixed Unit of Research U1039 Bioclinical Radiopharmaceuticals Grenoble France

5. Neuroscience Paris Seine National Institute of Health and Medical Research Mixed Unit of Research 1130/National Center for Scientific Research Mixed Unit of Research 8246 Sorbonne University Paris France

6. Department of Psychiatry Douglas Hospital McGill University Montreal Quebec Canada

Funder

Agence Nationale de la Recherche

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Reference53 articles.

1. The role of dopamine in epilepsy

2. Seizures and the basal ganglia: a review of the clinical data;Vercueil L;Epileptic Disord,2002

3. PET evidence for a role of the basal ganglia in patients with ring chromosome 20 epilepsy

4. Involvement of the basal ganglia in refractory epilepsy: an 18F‐fluoro‐L‐DOPA PET study using 2 methods of analysis;Bouilleret V;J Nucl Med,2005

5. Alteration of dopamine D2/D3 receptor binding in patients with juvenile myoclonic epilepsy

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