Tetrahydrobiopterin redox cycling in nitric oxide synthase: evidence supports a through-heme electron delivery
Author:
Affiliation:
1. Department of Pathobiology; Lerner Research Institute; The Cleveland Clinic; OH USA
2. Department of Chemistry and Biochemistry; Kent State University; OH USA
Funder
National Institutes of Health
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/febs.13933/fullpdf
Reference50 articles.
1. NO synthase: structures and mechanisms;Daff;Nitric Oxide,2010
2. Nitric-oxide synthase: a cytochrome P450 family foster child;Gorren;Biochim Biophys Acta,2007
3. Tetrahydrobiopterin radical enzymology;Wei;Chem Rev,2003
4. Structure and chemistry of cytochrome P450;Denisov;Chem Rev,2005
5. Tetrahydrobiopterin, a cofactor for rat cerebellar nitric-oxide synthase, does not function as a reactant in the oxygenation of arginine;Giovanelli;Proc Natl Acad Sci USA,1991
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