Dapsone-induced agranulocytosis-possible involvement of low-activity N -acetyltransferase 2

Author:

Potočnjak Ines1ORCID,Likić Robert23,Šimić Iveta23,Juričić Nahal Danica3,Čegec Ivana3,Ganoci Lana24,Božina Nada24

Affiliation:

1. Clinical Unit of Clinical Pharmacology and Toxicology; Department of Medicine; University Hospital Centre Sisters of Charity; Vinogradska cesta 10 000 Zagreb Croatia

2. University of Zagreb School of Medicine; Šalata 3 10 000 Zagreb Croatia

3. Division of Clinical Pharmacology; Department of Internal Medicine; University Hospital Centre Zagreb; Kišpatićeva 12 10 000 Zagreb Croatia

4. Department of Laboratory Diagnostics; University Hospital Centre Zagreb; Kišpatićeva 12 10 000 Zagreb Croatia

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference33 articles.

1. UpToDate® Wolters Kluwer Health www.uptodate.com

2. Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes;Coleman;Br. J. Clin. Pharmacol.,1989

3. Clinical pharmacokinetics of dapsone;Zuidema;Clin. Pharmacokinet.,1986

4. Current understanding of the mechanisms of idiosyncratic drug-induced agranulocytosis;Johnston;Expert Opin. Drug Metab. Toxicol.,2015

5. Dapsone-mediated agranulocytosis: risks, possible mechanisms and prevention;Coleman;Toxicology,2001

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