Lead Optimization on Conventional Non-Steroidal Anti-Inflammatory Drugs: An Approach to Reduce Gastrointestinal Toxicity-Reference-Cited by-同舟云学术

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Lead Optimization on Conventional Non-Steroidal Anti-Inflammatory Drugs: An Approach to Reduce Gastrointestinal Toxicity

Published:2014-03-13 Issue:1 Volume:84 Page:1-23
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Narsinghani Tamanna¹,Sharma Rajesh¹

Affiliation:

1. School of Pharmacy; Devi Ahilya Vishwavidyalaya; Takshashila Campus, Ring Road Indore 452 001 MP India

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12292/fullpdf

Reference76 articles.

1. Gastrointestinal and cardiovsacular risks of nonsteroidal anti-inflammatory drugs;Jones;Am J Med,2008

2. Markedly reduced gastrointestinal toxicity of a diclofenac derivative;Reuter;Life Sci,1994

3. Comparative model studies of gastric toxicity of nonsteroidal anti-inflammatory drugs;Markiewicz;Langmuir,2011

4. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs;Vane;Nature,1971

5. Nonsteroidal anti-inflammatory drugs-differences and similarities;Brooks;New Engl J Med,1991

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