1-Thia-4,7-diaza-spiro[4.4]nonane-3,6-dione: A Structural Motif for 5-hydroxytryptamine 6 Receptor Antagonism
Author:
Affiliation:
1. Cephalon, Inc.; 145 Brandywine Parkway West Chester PA 19380-4245 USA
Publisher
Wiley
Subject
Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12240/fullpdf
Reference13 articles.
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3. Potential role of the 5-HT6 receptor in depression and anxiety: an overview of clinical data;Wesołowska;Pharmacol Rep,2010
4. Activation of 5-HT6 receptors modulates sleep-wake activity and hippocampal theta oscillation;Ly;ACS Chem Neurosci,2013
5. 5-HT6 receptor antagonists as potential therapeutics for cognitive impairment;Rossé;Curr Top Med Chem,2010
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