Monte‐Carlo simulation of a thick lens IOL power calculation

Author:

Langenbucher Achim1ORCID,Szentmáry Nóra23ORCID,Cayless Alan4,Gatinel Damien5,Debellemanière Guillaume5,Wendelstein Jascha167ORCID,Hoffmann Peter8

Affiliation:

1. Department of Experimental Ophthalmology Saarland University Homburg/Saar Germany

2. Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Aniridia Research Saarland University Homburg/Saar Germany

3. Department of Ophthalmology Semmelweis‐University Budapest Hungary

4. School of Physical Sciences The Open University Milton Keynes UK

5. Rothschild Foundation Hospital Paris France

6. Institut für Refraktive‐ und Ophthalmo‐Chirurgie (IROC) Zurich Switzerland

7. Department of Ophthalmology Johannes Kepler University Linz Linz Austria

8. Augen‐ und Laserklinik Castrop‐Rauxel Castrop‐Rauxel Germany

Abstract

AbstractBackgroundThe purpose of this Monte‐Carlo study is to investigate the effect of using a thick lens model instead of a thin lens model for the intraocular lens (IOL) on the resulting refraction at the spectacle plane and on the ocular magnification based on a large clinical data set.MethodsA pseudophakic model eye with a thin spectacle correction, a thick cornea (curvatures for both surfaces and central thickness) and a thick IOL (equivalent power PL derived from a thin lens IOL, Coddington factor CL (uniformly distributed from −1.0 to 1.0), either preset central thickness LT = 0.9 mm (A) or optic edge thickness ET = 0.2 mm, (B)) was set up. Calculations were performed on a clinical data set containing 21 108 biometric measurements of a cataractous population based on linear Gaussian optics to derive spectacle refraction and ocular magnification using the thin and thick lens IOL models.ResultsA prediction model (restricted to linear terms without interactions) was derived based on the relevant parameters identified with a stepwise linear regression approach to provide a simple method for estimating the change in spectacle refraction and ocular magnification where a thick lens IOL is used instead of a thin lens IOL. The change in spectacle refraction using a thick lens IOL with (A) or (B) instead of a thin lens IOL with identical power was within limits of around ±1.5 dpt when the thick lens IOL was placed with its haptic plane at the plane of the thin lens IOL. In contrast, the change in ocular magnification from considering the IOL as a thick lens instead of a thin lens was small and not clinically significant.ConclusionThis Monte‐Carlo simulation shows the impact of using a thick lens model IOL with preset LT or ET on the resulting spherical equivalent refraction and ocular magnification. If IOL manufacturers would provide all relevant data on IOL design data and refractive index for all power steps, this would make it possible to perform direct calculations of refraction and ocular magnification.

Publisher

Wiley

Subject

Ophthalmology,General Medicine

Reference28 articles.

1. The PEARL-DGS Formula: The Development of an Open-source Machine Learning–based Thick IOL Calculation Formula

2. Comparison of 2 swept-source optical coherence tomography–based biometry devices

3. Calculation of the optical power of intraocular lenses;Fyodorov S.N.;Investigative Ophthalmology,1975

4. Determining the Theoretical Effective Lens Position of Thick Intraocular Lenses for Machine Learning–Based IOL Power Calculation and Simulation

5. GernetH OstholtH&WernerH(1970)Die präoperative Berechnung intraocularer Binkhorst‐Linsen. 122. Vers. d. Ver. Rhein.‐Westfäl. Augenärzte. Balve Verlag Zimmermann Germany pp.54‐55.

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