Safety, tolerability and pharmacokinetics of emodepside, a potential novel treatment for onchocerciasis (river blindness), in healthy male subjects
Author:
Affiliation:
1. Drugs for Neglected Diseases initiative (DNDi) Geneva Switzerland
2. Hammersmith Medicines Research Ltd London UK
3. Invicro, Burlington Danes Building Imperial College London, Hammersmith Hospital London UK
4. Bayer AG Wuppertal Germany
Funder
Bill and Melinda Gates Foundation
Bundesministerium für Bildung und Forschung
United States Agency for International Development
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.14816
Reference20 articles.
1. World Health Organisation.Onchocerciasis (river blindness) ‐ DiseaseInformationhttps://www.who.int/blindness/partnerships/onchocerciasis_disease_information/en/consultedon 14 April2020
2. Research for new drugs for elimination of onchocerciasis in Africa
3. Onchocerciasis Elimination: Progress and Challenges;Lakwo T;Res Rep Trop Med,2020
4. Phenotypic Evidence of Emerging Ivermectin Resistance in Onchocerca volvulus
5. Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial
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