Production of high-quality islets from goettingen minipigs: Choice of organ preservation solution, donor pool, and optimal cold ischemia time

Author:

Steffen Anja12,Kiss Thomas3,Schmid Janine1,Schubert Undine1,Heinke Sophie1,Lehmann Susann1,Bornstein Stefan1245,Ludwig Barbara124,Ludwig Stefan6

Affiliation:

1. Department of Medicine III; University Hospital Carl Gustav Carus; Technische Universität Dresden; Dresden Germany

2. Paul Langerhans Institute Dresden of Helmholtz Centre Munich at University Clinic Carl Gustav Carus of TU Dresden Faculty of Medicine; Technische Universität Dresden; DZD-German Centre for Diabetes Research; Dresden Germany

3. Department of Anesthesiology and Intensive Care Medicine; University Hospital Carl Gustav Carus; Technische Universität Dresden; Dresden Germany

4. Center for Regenerative Therapies; Technische Universität Dresden; Dresden Germany

5. Diabetes and Nutritional Sciences; Rayne Institute; King's College London; London UK

6. Department of Visceral-, Thoracic- and Vascular Surgery; University Hospital Carl Gustav Carus; Technische Universität Dresden; Dresden Germany

Publisher

Wiley

Subject

Transplantation,Immunology

Reference39 articles.

1. Current status of islet xenotransplantation;Park;Int J Surg,2015

2. Justifying clinical trials for porcine islet xenotransplantation;Ellis;Xenotransplantation,2015

3. Xenotransplantation of porcine islet cells as a potential option for the treatment of type 1 diabetes in the future;Reichart;Horm Metab Res,2015

4. Use of the Göttingen minipig as a model of diabetes, with special focus on type 1 diabetes research;Larsen;ILAR J,2004

5. Extended microbiological characterization of Goettingen minipigs in the context of xenotransplantation: detection and vertical transmission of hepatitis e virus;Morozov;PLoS ONE,2015

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