Long‐term efficacy of opicapone in fluctuating Parkinson's disease patients: a pooled analysis of data from two phase 3 clinical trials and their open‐label extensions

Author:

Ferreira J. J.12,Lees A.3,Rocha J.‐F.4ORCID,Poewe W.5,Rascol O.6,Soares‐da‐Silva P.478

Affiliation:

1. Faculty of Medicine Instituto de Medicina Molecular University of Lisbon Lisbon Torres Vedras Portugal

2. CNS ‐ Campus Neurológico Sénior Torres Vedras Portugal

3. Reta Lila Weston Institute University College London London UK

4. Department of Research and Development BIAL – Portela & Ca SA S. Mamede do Coronado Portugal

5. Department of Neurology Medical University Innsbruck Innsbruck Austria

6. Clinical Investigation Centre CIC1436 Departments of Clinical Pharmacology and Neurosciences NS‐Park/FCRIN Network University Hospital of Toulouse INSERM University Toulouse 3 Toulouse France

7. Department of Pharmacology and Therapeutics Faculty of Medicine University Porto PortoPortugal

8. Center for Drug Discovery and Innovative Medicines MedInUP University Porto Porto Portugal

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Reference7 articles.

1. Ongentys.Summary of Product Characteristics2018. Available for download at:https://www.ema.europa.eu/documents/product-information/ongentys-epar-product-information_en.pdf(accessed 18/12/2018).

2. Opicapone as an adjunct to levodopa in patients with Parkinson's disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial

3. Opicapone as Adjunct to Levodopa Therapy in Patients With Parkinson Disease and Motor Fluctuations

4. Effectiveness of opicapone and switching from entacapone in fluctuating Parkinson disease

5. European Medicines Agency.Ongentys Assessment Report.2016. Procedure No. EMEA/H/C/002790/0000. Available for download at:https://www.ema.europa.eu/en/medicines/human/EPAR/ongentys(accessed 18/12/2018).

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