Donepezil Reverses Dendritic Spine Morphology Adaptations and Fmr1 Epigenetic Modifications in Hippocampus of Adult Rats After Adolescent Alcohol Exposure

Author:

Mulholland Patrick J.1,Teppen Tara L.2,Miller Kelsey M.3,Sexton Hannah G.3,Pandey Subhash C.2,Swartzwelder H. Scott3ORCID

Affiliation:

1. Departments of Neuroscience and Psychiatry & Behavioral Sciences; Charleston Alcohol Research Center; Charleston South Carolina

2. Center for Alcohol Research in Epigenetics; Department of Psychiatry; University of Illinois at Chicago and Jesse Brown VA Medical Center; Chicago Illinois

3. Department of Psychiatry and Behavioral Sciences; Duke University Medical Center and Durham VA Medical Center; Durham North Carolina

Funder

National Institute on Alcohol Abuse and Alcoholism

U.S. Department of Veterans Affairs

Publisher

Wiley

Subject

Psychiatry and Mental health,Toxicology,Medicine (miscellaneous)

Reference85 articles.

1. Impairment of semantic and figural memory by acute ethanol: age-dependent effects;Acheson;Alcohol Clin Exp Res,1998

2. Enhanced dendritic spine number of neurons of the prefrontal cortex, hippocampus, and nucleus accumbens in old rats after chronic donepezil administration;Alcantara-Gonzalez;Synapse,2010

3. Combined administration of cerebrolysin and donepezil induces plastic changes in prefrontal cortex in aged mice;Alcantara-Gonzalez;Synapse,2012

4. Development of cholinergic neurons in the septal/diagonal band complex of the rat;Armstrong;Brain Res,1987

5. A novel cholinergic induction of long-term potentiation in rat hippocampus;Auerbach;J Neurophysiol,1994

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