Progressive multifocal leukoencephalopathy in a patient with relapsing multiple sclerosis treated with ocrelizumab: A case report-Reference-Cited by-同舟云学术

Progressive multifocal leukoencephalopathy in a patient with relapsing multiple sclerosis treated with ocrelizumab: A case report

Published:2023-07-31 Issue:10 Volume:30 Page:3357-3361
ISSN:1351-5101
Container-title:European Journal of Neurology
language:en
Short-container-title:Euro J of Neurology

Author:

Puig‐Casadevall Marc¹,Álvarez‐Bravo Gary¹²^ORCID,Varela Ana Quiroga²³,Robles‐Cedeño René¹³⁴,Sànchez Cirera Laura⁵^ORCID,Miguela Albert²³,Laguillo Gemma⁶,Montalban Xavier⁷,Hauser Stephen L.⁸,Ramió‐Torrentà Lluis¹²³⁴⁵

Affiliation:

1. Girona Neuroimmunology and Multiple Sclerosis Unit, Neurology Department Dr. Josep Trueta University Hospital and Santa Caterina Hospital Salt Spain

2. Neurodegeneration and Neuroinflammation Research Group Girona Biomedical Research Institute (IDIBGI) Salt Spain

3. Instituto de Salud Carlos III, Redes de Investigación Cooperativa Orientada a Resultados en Salud (RICORS), Red de Enfermedades inflamatorias (RD21/0002/0063) Madrid Spain

4. Medical Sciences Department University of Girona Girona Spain

5. Neurology Department Dr. Josep Trueta University Hospital Girona Spain

6. Radiology Department Dr. Josep Trueta University Hospital Girona Spain

7. Servei de Neurologia‐Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Vall d'Hebron Institut de Recerca Vall d'Hebron Hospital Universitari, Universitat Autònoma de Barcelona Barcelona Spain

8. Department of Neurology University of California San Francisco California USA

Abstract

AbstractIntroductionProgressive multifocal leukoencephalopathy is a rare but often fatal complication of some multiple sclerosis treatments. Although it has mainly been associated with natalizumab treatment, its appearance with other immunosuppressive therapies has also been reported.AimsThe aim of this case report is to describe the development of progressive multifocal encephalopathy in a patient with relapsing–remitting multiple sclerosis treated with ocrelizumab without previous use of natalizumab.ConclusionsA summary of the presentation and disease course is provided, presented in the context of the current literature and likely pathophysiology.

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/ene.15988

Reference15 articles.

1. Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

2. PROGRESSIVE MULTIFOCAL LEUKO-ENCEPHALOPATHY

3. Clinical outcomes of natalizumab-associated progressive multifocal leukoencephalopathy

4. Progressive multifocal leukoencephalopathy in dimethyl fumarate-treated multiple sclerosis patients

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