Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif-Reference-Cited by-同舟云学术

Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif

Published:2014-01-15 Issue:4 Volume:281 Page:1017-1028
ISSN:1742-464X
Container-title:FEBS Journal
language:en
Short-container-title:FEBS J

Author:

Fells James I.¹,Lee Sue Chin¹,Norman Derek D.¹,Tsukahara Ryoko¹,Kirby Jason R.²,Nelson Sandra²,Seibel William²,Papoian Ruben²,Patil Renukadevi³,Miller Duane D.³,Parrill Abby L.⁴,Pham Truc-Chi⁴,Baker Daniel L.⁴,Bittman Robert⁵,Tigyi Gabor¹

Affiliation:

1. Department of Physiology; College of Medicine; University of Tennessee Health Science Center; Memphis TN USA

2. Drug Discovery Center; University of Cincinnati; OH USA

3. Department of Pharmaceutical Sciences; College of Pharmacy; University of Tennessee Health Science Center; Memphis TN USA

4. Computational Research on Materials Institute; Department of Chemistry; University of Memphis; TN USA

5. Department of Chemistry and Biochemistry; Queens College of The City University of New York; Flushing NY USA

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/febs.12674/fullpdf

Reference25 articles.

1. Autotaxin and LPA receptor signaling in cancer;Houben;Cancer Metastasis Rev,2011

2. Autotaxin - an LPA producing enzyme with diverse functions;Nakanaga;J Biochem,2010

3. Biological roles of lysophosphatidic acid signaling through its production by autotaxin;Okudaira;Biochimie,2010

4. ATX-LPA receptor axis in inflammation and cancer;Liu;Cell Cycle,2009

5. Regulation and biological activities of the autotaxin-LPA axis;Meeteren;Prog Lipid Res,2007

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