BCAT1, a key prognostic predictor of hepatocellular carcinoma, promotes cell proliferation and induces chemoresistance to cisplatin

Author:

Zheng Yi-Hu1,Hu Wei-Jian1,Chen Bi-Cheng2,Grahn Tan-Hooi-Min3,Zhao Yan-Rong1,Bao Hai-Li1,Zhu Ye-Fan1,Zhang Qi-Yu12

Affiliation:

1. Department of General Surgery; The First Affiliated Hospital of Wenzhou Medical University; Wenzhou China

2. Key Laboratory of Surgery; The First Affiliated Hospital of Wenzhou Medical University; Wenzhou China

3. Department of Molecular Medicine and Gene Therapy; Lund University; Lund Sweden

Funder

Zhejiang Provincial Top Key Discipline in Surgery

Wenzhou Key Laboratory Project in Surgery

Publisher

Wiley

Subject

Hepatology

Reference18 articles.

1. Oral supplementation of branched-chain amino acids reduces early recurrence after hepatic resection in patients with hepatocellular carcinoma: a prospective study;Ichikawa;Surg Today,2013

2. Branched-chain amino acids prevent hepatocarcinogenesis and prolong survival of patients with cirrhosis;Kawaguchi;Clin Gastroenterol Hepatol,2014

3. Cloning of the rat and human mitochondrial branched chain aminotransferases (BCATm);Bledsoe;Biochim Biophys Acta,1997

4. Branched chain aminotransferase isoenzymes. Purification and characterization of the rat brain isoenzyme;Hall;J Biol Chem,1993

5. Isozyme patterns of branched-chain amino acid transaminase in various rat hepatomas;Ogawa;Cancer Res,1972

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