1. Department of Internal Medicine I; Johann Wolfgang Goethe-University Hospital; Frankfurt Germany
2. Institute of Biostatistics and Mathematical Modeling; Johann Wolfgang Goethe-University; Frankfurt Germany
3. Dr Senckenberg Institute of Pathology; Johann Wolfgang Goethe-University Hospital; Frankfurt Germany
4. Department of General and Visceral Surgery; Johann Wolfgang Goethe-University Hospital; Frankfurt Germany
5. German Cancer Research Center (DKFZ); Heidelberg Germany