A case study of 10 patients administered HBOC‐201 in high doses over a prolonged period: outcomes during severe anemia when transfusion is not an option-Reference-Cited by-同舟云学术

A case study of 10 patients administered HBOC‐201 in high doses over a prolonged period: outcomes during severe anemia when transfusion is not an option

Published:2020-05 Issue:5 Volume:60 Page:932-939
ISSN:0041-1132
Container-title:Transfusion
language:en
Short-container-title:Transfusion

Author:

Zumberg Marc¹^ORCID,Gorlin Jed²^ORCID,Griffiths Elizabeth A.³,Schwartz Garry⁴,Fletcher Bradley S.⁵,Walsh Katherine⁶,Dao Kim‐Hien⁷,Vansandt Amanda⁸,Lynn Mauricio⁹,Shander Aryeh¹⁰

Affiliation:

1. Division of Hematology/OncologyUniversity of Florida Shands Cancer Hospital Gainesville Florida USA

2. Transfusion Service, Hennepin County Medical CenterUniversity of Minnesota Minneapolis Minnesota USA

3. Department of MedicineRoswell Park Comprehensive Cancer Center Buffalo New York USA

4. Levine Cancer Institute Concord North Carolina USA

5. Division of Hematology and OncologyUniversity of Florida Shands Cancer Hospital Gainesville Florida USA

6. Division of HematologyThe Ohio State University Comprehensive Cancer Center Columbus Columbus Ohio USA

7. Knight Cancer Institute, Oregon Health & Science University Portland Oregon USA

8. Department of PathologyOregon Health & Science University Portland Portland Oregon USA

9. Ryder Trauma Center, Jackson Memorial HospitalUniversity of Miami Medical School Miami Florida USA

10. Department of AnesthesiologyCritical Care Medicine, Pain Management and Hyperbaric Medicine, Team Health Research Institute, Englewood Medical Center Englewood New Jersey USA

Funder

HBO2 Therapeutics, LLC

Publisher

Wiley

Subject

Hematology,Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/trf.15778

Reference50 articles.

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2. Relative efficacies of HBOC‐201 and polyheme to increase oxygen transport compared to blood and crystalloids. “2017 Military Supplement.”;Dubé GP;Shock,2017

3. Facing coagulation disorders after acute trauma;Mullier F;B‐ENT,2016

4. Addressing the unmet need of life‐threatening anemia with hemoglobin‐based oxygen carriers

5. HBOC-201 as an Alternative to Blood Transfusion: Efficacy and Safety Evaluation in a Multicenter Phase III Trial in Elective Orthopedic Surgery

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