Tramadol can selectively manage moderate pain in children following European advice limiting codeine use

Author:

Marzuillo Pierluigi1,Calligaris Lorenzo2,Barbi Egidio2

Affiliation:

1. M.D. Department of Women and Children and General and Specialized Surgery; Seconda Università degli Studi di Napoli; Naples Italy

2. M.D. Institute for Maternal and Child Health IRCCS Burlo Garofolo; Trieste Italy

Publisher

Wiley

Subject

General Medicine,Pediatrics, Perinatology and Child Health

Reference60 articles.

1. European Medicines Agency (EMA) Review of codeine-containing medicines 2012 http://www.ema.europa.eu/docs/en_GB/document_library/Referrals_document/Codeine_containing_medicinal_products/Procedure_started/WC500133297.pdf

2. Current practice and recent advances in pediatric pain management;Chiaretti;Eur Rev Med Pharmacol Sci,2013

3. Tramadol as an analgesic for mild to moderate cancer pain;Leppert;Pharmacol Rep,2009

4. Tramadol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states;Lee;Drugs,1993

5. Pharmacokinetics of oral tramadol drops for postoperative pain relief in children aged 4 to 7 years-a pilot study;Payne;Anesth Prog,2002

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