Celecoxib attenuates hepatic cirrhosis through inhibition of epithelial-to-mesenchymal transition of hepatocytes

Author:

Wen Shi-Lei12,Gao Jin-Hang2,Yang Wen-Juan3,Lu Yao-Yao3,Tong Huan3,Huang Zhi-Yin3,Liu Zhang-Xu4,Tang Cheng-Wei23

Affiliation:

1. Regenerative Medicine Research Center; West China Hospital; Chengdu China

2. Division of Peptides Related with Human Diseases; State Key Laboratory of Biotherapy; Sichuan University; Chengdu China

3. Department of Gastroenterology; West China Hospital; Chengdu China

4. Research Center for Liver Diseases; Keck School of Medicine; University of Southern California; Los Angeles California USA

Funder

Natural Science Fund of China

Publisher

Wiley

Subject

Gastroenterology,Hepatology

Reference48 articles.

1. Pathogenesis of liver fibrosis;Hernandez-Gea;Annu. Rev. Pathol.,2011

2. Reversibility of liver fibrosis;Pellicoro;Fibrogenesis. Tissue. Repair.,2012

3. Hepatic fibrosis;Jiao;Curr. Opin. Gastroenterol.,2009

4. Targeting liver fibrosis: strategies for development and validation of antifibrotic therapies;Schuppan;Hepatology.,2009

5. Defining therapeutic targets for liver fibrosis: exploiting the biology of inflammation and repair;Iredale;Pharmacol. Res.,2008

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