Does ivacaftor interfere with the antimicrobial activity of commonly used antibiotics against Pseudomonas aeruginosa ?-Results of an in vitro study-Reference-Cited by-同舟云学术

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Does ivacaftor interfere with the antimicrobial activity of commonly used antibiotics against Pseudomonas aeruginosa ?-Results of an in vitro study

Published:2018-06-29 Issue:6 Volume:43 Page:836-843
ISSN:0269-4727
Container-title:Journal of Clinical Pharmacy and Therapeutics
language:en
Short-container-title:J Clin Pharm Ther

Author:

Millar B. C.¹²,Rendall J. C.³,Downey D. G.³⁴,Moore J. E.¹²³⁴

Affiliation:

1. Northern Ireland Public Health Laboratory; Department of Bacteriology; Belfast City Hospital; Belfast UK

2. School of Biomedical Sciences; Ulster University; Coleraine UK

3. Northern Ireland Regional Adult Cystic Fibrosis Centre, Level 8; Belfast City Hospital; Belfast UK

4. Centre for Experimental Medicine; Queen's University; Belfast UK

Funder

Vertex Pharmaceuticals Inc, Boston, USA, through an Investigator Initiated Study (IIS) Grant.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/jcpt.12722/fullpdf

Reference20 articles.

1. The adult cystic fibrosis airway microbiota is stable over time and infection type, and highly resilient to antibiotic treatment of exacerbations;Fodor;PLoS ONE,2012

2. Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus;Doring;Eur Respir J,2000

3. Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis;Høiby;BMC Med,2011

4. Mucoid Pseudomonas in cystic fibrosis;Pritt;Am J Clin Path,2007

5. Pseudomonas aeruginosa displays an altered phenotype in vitro when grown in the presence of mannitol;Moore;Br J Biomed Sci,2015

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4. The Effect of CFTR Modulators on Airway Infection in Cystic Fibrosis;International Journal of Molecular Sciences;2022-03-23

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