Model‐based evaluation of pulmonary pharmacokinetics in asthmatic and COPD patients after oral olodaterol inhalation

Author:

Borghardt Jens Markus12,Weber Benjamin2,Staab Alexander2,Kunz Christina2,Kloft Charlotte1

Affiliation:

1. Institute of Pharmacy, Department of Clinical Pharmacy and BiochemistryFreie Universität Berlin 12169 Berlin Germany

2. Translational Medicine and Clinical PharmacologyBoehringer Ingelheim Pharma GmbH & Co. KG Biberach Germany

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference47 articles.

1. Global Initiative for Chronic Obstructive Lung Disease (GOLD).Global Strategy for the Diagnosis Management and Prevention of Chronic Obstructive Pulmonary Disease 2015. Available athttp://www.goldcopd.it/materiale/2015/GOLD_Report_2015.pdf

2. Global Initiative for Asthma (GINA).Global strategy for asthma management and prevention 2016.http://ginasthma.org/2016-gina-report-global-strategy-for-asthma-management-and-prevention/

3. The inhalation device influences lung deposition and bronchodilating effect of terbutaline.

4. Variability in lung deposition of inhaled drug, within and between asthmatic patients, with a pMDI and a dry powder inhaler, Turbuhaler®

5. Population pharmacokinetic analysis of tiotropium in healthy volunteers after intravenous administration and inhalation;Parra‐Guillen Z;J Pharmacokinet Pharmacodyn,2014

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