Five‐year neurodevelopmental assessment of extremely preterm or extremely low birthweight infants: Association with school performance

Author:

Wiingreen Rikke123ORCID,Greisen Gorm23ORCID,Esbjørn Barbara Hoff4,Løkkegaard Ellen C. L.35,Torp‐Pedersen Christian67,Sørensen Kathrine Kold67,Andersen Mikkel Porsborg68,Hansen Bo Mølholm13ORCID

Affiliation:

1. Department of Paediatrics Copenhagen University Hospital ‐ North Zealand Hilleroed Denmark

2. Department of Neonatology, Juliane Marie Center Copenhagen University Hospital – Rigshospitalet Copenhagen Denmark

3. Department of Clinical Medicine University of Copenhagen Copenhagen Denmark

4. Campus for Psychiatric Simulation Capital Region Psychiatry Ballerup Denmark

5. Department of Obstetrics and Gynecology Copenhagen University Hospital ‐ North Zealand Hilleroed Denmark

6. Department of Cardiology Copenhagen University Hospital ‐ North Zealand Hilleroed Denmark

7. Department of Public Health University of Copenhagen Copenhagen Denmark

8. The Prehospital Center Region Zealand Næstved Denmark

Abstract

AbstractAimWe investigated the associations between motor performance and IQ at 5 years of age and school difficulties and grade point averages (GPAs) at 18 years of age. Additionally, the accuracy of preschool IQ in predicting school difficulties was examined.MethodsA nationwide follow‐up study of children born in 1994–1995 who were <28 weeks of gestation or had a birthweight <1000 g. The Danish personal identification number was used to merge data from a national cohort study with population‐based registries. Logistic regression analyses examined the associations between motor performance/IQ and school difficulties. Linear regression analyses and the area under the receiver operator curve (AUC) were used to examine the relationship between IQ and GPAs.ResultsThe study population comprised 248 children, 37% were classified with school difficulties. Motor performance and IQ were associated with school difficulties. The odds of having school difficulties increased as IQ decreased, and the same pattern was observed for GPAs. IQ predicted school difficulties, with an AUC of 0.80 (confidence interval: 0.74–0.86).ConclusionPreschool motor performance and IQ were associated with school difficulties. Additionally, IQ was linked to GPAs. As a screening tool, the predictive ability of preschool IQ for academic difficulties was moderate/high in this cohort.

Funder

Aase og Ejnar Danielsens Fond

Ville Heises Legat

Else og Mogens Wedell Wedellsborgs Fond

Jascha Fonden

Publisher

Wiley

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