Time now to TORC the TORC? New developments in mTOR pathway inhibition in lymphoid malignancies
Author:
Affiliation:
1. Department of Haematology; Oxford University Hospitals NHS Trust; Oxford UK
2. Department of Haematology; University College Hospital; London UK
3. Department of Haematology; Royal Free Hospital; London UK
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bjh.12945/fullpdf
Reference134 articles.
1. Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action;Aguirre;The Journal of Biological Chemistry,2002
2. Rapamycin shows anticancer activity in primary chronic lymphocytic leukemia cells in vitro, as single agent and in drug combination;Aleskog;Leukemia & Lymphoma,2008
3. Dual mTORC2/mTORC1 targeting results in potent suppressive effects on acute myeloid leukemia (AML) progenitors;Altman;Clinical Cancer Research: An Official Journal of the American Association for Cancer Research,2011
4. Sirolimus, tacrolimus, and low-dose methotrexate as graft-versus-host disease prophylaxis in related and unrelated donor reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation;Alyea;Biology of Blood and Marrow Transplantation: Journal of the American Society for Blood and Marrow Transplantation,2008
5. Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group;Ansell;Cancer,2008
Cited by 41 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. DEPTOR levels in patients with mycosis fungoides;Dermatologica Sinica;2024-09-12
2. Multifaceted effects of LRP6 in cancer: exploring tumor development, immune modulation and targeted therapies;Medical Oncology;2024-06-19
3. DEPTOR levels in patients with mycosis fungoides;2023-11-25
4. A phase 2 and pharmacological study of sapanisertib in patients with relapsed and/or refractory acute lymphoblastic leukemia;Cancer Medicine;2023-11-13
5. Salinomycin sodium exerts anti diffuse large B-cell lymphoma activity through inhibition of LRP6-mediated Wnt/β-catenin and mTORC1 signaling;Leukemia & Lymphoma;2023-04-24
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3