Reversible deficits in apical transporter trafficking associated with deficiency in diacylglycerol acyltransferase

Author:

Schlegel Cameron12,Lapierre Lynne A.123,Weis Victoria G.12,Williams Janice A.4,Kaji Izumi12,Pinzon-Guzman Carolina12,Prasad Nripesh5,Boone Braden5,Jones Angela5,Correa Hernan6,Levy Shawn E.5,Han Xianlin7,Wang Miao7,Thomsen Kelly8,Acra Sari8,Goldenring James R.1239ORCID

Affiliation:

1. Department of Surgery; Vanderbilt University School of Medicine; Nashville Tennessee

2. The Epithelial Biology Center; Vanderbilt University School of Medicine; Nashville Tennessee

3. The Nashville VA Medical Center; Nashville Tennessee

4. Cell Imaging Share Resource; Vanderbilt University School of Medicine; Nashville Tennessee

5. HudsonAlpha Institute for Biotechnology; Huntsville Alabama

6. Department of Pathology, Microbiology and Immunology; Vanderbilt University School of Medicine; Nashville Tennessee

7. Departments of Medicine & Biochemistry, Barshop Institute for Longevity and Aging Studies; University of Texas Health; San Antonio Texas

8. Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics; Vanderbilt University School of Medicine; Nashville Tennessee

9. Department of Cell & Developmental Biology; Vanderbilt University School of Medicine; Nashville Tennessee

Funder

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Cancer Institute

National Center for Advancing Translational Sciences

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology

Reference25 articles.

1. Congenital diarrheal disorders: an updated diagnostic approach;Terrin;Int J Mol Sci,2012

2. Diarrhea in neonatal intensive care unit;Passariello;World J Gastroenterol,2010

3. Congenital diarrheal disorders: improved understanding of gene defects is leading to advances in intestinal physiology and clinical management;Berni Canani;J Pediatr Gastroenterol Nutr,2010

4. Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis;Yen;J Lipid Res,2008

5. DGAT1 mutation is linked to a congenital diarrheal disorder;Haas;J Clin Invest,2012

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