Tolerance and Pharmacokinetics of Galliprant™ Administered Orally to Collies Homozygous for MDR1‐1Δ-Reference-Cited by-同舟云学术

Tolerance and Pharmacokinetics of Galliprant™ Administered Orally to Collies Homozygous for MDR1‐1Δ

Published:2021-07-04 Issue:5 Volume:44 Page:705-713
ISSN:0140-7783
Container-title:Journal of Veterinary Pharmacology and Therapeutics
language:en
Short-container-title:J Vet Pharmacol Therap

Author:

Heit Mark C.¹,Mealey Katrina L.²,King Stephen B.¹

Affiliation:

1. Elanco Animal Health, Inc Greenfield IN USA

2. Progam in Individualized Medicine (PrIMe) College of Veterinary Medicine Washington State University Pullman WA USA

Funder

Elanco Animal Health

Publisher

Wiley

Subject

General Veterinary,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jvp.12984

Reference19 articles.

1. Biliary excretion of technetium-99m-sestamibi in wild-type dogs and in dogs with intrinsic (ABCB1-1Δ mutation) and extrinsic (ketoconazole treated) P-glycoprotein deficiency

2. The Effect of the Canine ABCB1 ‐1Δ Mutation on Sedation after Intravenous Administration of Acepromazine

3. European Medcines Agency(2020). Retrieved from.https://www.ema.europa.eu/en/documents/product‐information/galliprant‐epar‐product‐information_en.pdf

4. FDACVM. (2020 July 14).Guidance for Industry #85. Good Clinical Practice VICH GL9. Recommended for Implementation at Step 7 of the VICH Process on 15 June 2000 by the VICH Steering Committee. Final Guidance May 9 2001; revised on June 8 2011.

5. Immunohistochemical Detection of P-glycoprotein in Formalin-fixed and Paraffin-embedded Normal and Neoplastic Canine Tissues

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