Review article: Advances in the management of lower gastrointestinal bleeding

Author:

Alali Ali A.1ORCID,Almadi Majid A.23,Barkun Alan N.34ORCID

Affiliation:

1. Department of Medicine, Faculty of Medicine Kuwait University Jabriya Kuwait

2. Division of Gastroenterology King Khalid University Hospital, King Saud University Riyadh Saudi Arabia

3. Division of Gastroenterology The McGill University Health Center, Montreal General Hospital, McGill University Montreal Canada

4. Division of Clinical Epidemiology The McGill University Health Center, Montreal General Hospital, McGill University Montreal Canada

Abstract

SummaryBackgroundLower gastrointestinal bleeding (LGIB) is a common emergency with substantial associated morbidity and mortality. Elective colonoscopy plays an essential role in management, with an even more important role for radiology in the acute setting. Recent advances in the management of patients with LGIB warrant review as the management has recently evolved.AimsTo provide a comprehensive and updated overview of advances in the approach to patients with LGIBMethodsWe performed a comprehensive literature search to examine the current data for this narrative review supplemented by expert opinion.ResultsThe incidence of LGIB is increasing worldwide, partly related to an ageing population and the increasing use of antithrombotics. Diverticulosis continues to be the most common aetiology of LGIB. Pre‐endoscopic risk stratification tools, especially the Oakland score, can aid appropriate patient triage. Adequate resuscitation continues to form the basis of management, while appropriate management of antithrombotics is crucial to balance the risk of worsening bleeding against increased cardiovascular risk. Radiological imaging plays an essential role in the diagnosis and treatment of acute LGIB, especially among unstable patients. Colonoscopy remains the gold‐standard test for the elective management of stable patients.ConclusionsThe management of LGIB has evolved significantly in recent years, with a shift towards radiological interventions for unstable patients while reserving elective colonoscopy for stable patients. A multidisciplinary approach is essential to optimise the outcomes of patients with LGIB.

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

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