Current status of non‐invasive prenatal testing in Japan

Author:

Samura Osamu1ORCID,Sekizawa Akihiko2,Suzumori Nobuhiro3ORCID,Sasaki Aiko4,Wada Seiji4,Hamanoue Haruka5,Hirahara Fumiki5,Sawai Hideaki6,Nakamura Hiroaki7,Yamada Takahiro8,Miura Kiyonori9,Masuzaki Hideaki9,Nakayama Setsuko10,Okai Takashi10,Kamei Yoshimasa11,Namba Akira11,Murotsuki Jun12,Tanemoto Tomohiro1,Fukushima Akimune13,Haino Kazufumi14,Tairaku Shinya15,Matsubara Keiichi16,Maeda Kazuhisa17,Kaji Takashi18,Ogawa Masanobu19,Osada Hisao20,Nishizawa Haruki21,Okamoto Yoko22,Kanagawa Takeshi2223,Kakigano Aiko23,Kitagawa Michihiro24,Ogawa Masaki25,Izumi Shunichiro26,Katagiri Yukiko27,Takeshita Naoki28,Kasai Yasuyo29,Naruse Katsuhiko30,Neki Reiko31,Masuyama Hisashi32,Hyodo Maki33,Kawano Yukie34,Ohba Takashi35,Ichizuka Kiyotake36,Kido Yasuhiro37,Fukao Toshiyuki38,Miharu Norio39,Nagamatsu Takeshi40,Watanabe Atsushi41,Hamajima Naoki42,Hirose Masaya43,Sanui Ayako44,Shirato Nahoko2,Yotsumoto Junko45,Nishiyama Miyuki4,Hirose Tatsuko2,Sago Haruhiko4ORCID

Affiliation:

1. Department of Obstetrics and Gynecology Jikei University School of Medicine Tokyo Japan

2. Department of Obstetrics and Gynecology Showa University School of Medicine Tokyo Japan

3. Division of Clinical and Molecular Genetics, Department of Obstetrics and Gynecology Nagoya City University Nagoya Japan

4. Center of Maternal–Fetal, Neonatal and Reproductive Medicine National Center for Child Health and Development Tokyo Japan

5. Department of Human Genetics Yokohama City University Graduate School of Medicine Yokohama, Kanagawa Japan

6. Department of Obstetrics and Gynecology Hyogo College of Medicine Nishinomiya, Hyogo Japan

7. Department of Obstetrics Osaka City General Hospital Osaka City, Osaka Japan

8. Department of Obstetrics and Gynecology Hokkaido University Graduate School of Medicine Sapporo, Hokkaido Japan

9. Department of Obstetrics and Gynecology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan

10. Maternal and Child Health Center Aiiku Hospital Tokyo Japan

11. Departments of Obstetrics and Gynecology Saitama Medical University School of Medicine Moroyama, Iruma, Saitama Japan

12. Department of Maternal and Fetal Medicine Tohoku University Graduate School of Medicine, Miyagi Children's Hospital Sendai, Miyagi Japan

13. Departments of Obstetrics and Gynecology Iwate Medical University School of Medicine Morioka, Iwate Japan

14. Department of Obstetrics and Gynecology Niigata University Medical and Dental Hospital Niigata Japan

15. Department of Obstetrics and Gynecology Kobe University Graduate School of Medicine Kobe, Hyogo Japan

16. Department of Obstetrics and Gynecology Ehime University School of Medicine Matsuyama, Ehime Japan

17. Department of Obstetrics and Gynecology Shikoku Medical Center for Children and Adults Zentsuji, Kagawa Japan

18. Department of Obstetrics and Gynecology University of Tokushima Faculty of Medicine Tokushima Japan

19. Department of Obstetrics and Gynecology, Clinical Research Institute National Hospital Organization Kyushu Medical Center Fukuoka Japan

20. Department of Obstetrics and Gynecology Chiba University Graduate School of Medicine Chiba Japan

21. Department of Obstetrics and Gynecology Fujita Health University Toyoake, Aichi Japan

22. Department of Obstetrics Osaka Medical Center and Research Institute for Maternal and Child Health Izumi, Osaka Japan

23. Department of Obstetrics and Gynecology Osaka University Faculty of Medicine Suita, Osaka Japan

24. Sanno Hospital Tokyo Japan

25. Perinatal Medical Center Tokyo Women's Medical University Hospital Tokyo Japan

26. Department of Obstetrics and Gynecology Tokai University School of Medicine Hiratsuka, Kanagawa Japan

27. Department of Obstetrics and Gynecology Toho University Omori Medical Center Tokyo Japan

28. Toho University Omori Medical Center Tokyo Japan

29. Department of Obstetrics and Gynecology Japanese Red Cross Medical Center Tokyo Japan

30. Department of Obstetrics and Gynecology Nara Medical University Kashihara, Nara Japan

31. Department of Perinatology and Gynecology National Cerebral and Cardiovascular Center Suita, Osaka Japan

32. Department of Obstetrics and Gynecology Okayama University Graduate School of Medicine Okayama Japan

33. Department of Obstetrics and Gynecology Hiroshima University Graduate School of Medicine Hiroshima Japan

34. Department of Molecular Pathology, Faculty of Medicine Oita University Oita Japan

35. Department of Obstetrics and Gynecology Kumamoto University Kumamoto Japan

36. Department of Obstetrics and Gynecology Showa University Northern Yokohama Hospital Yokohama, Kanagawa Japan

37. Division of Clinical Genetics Dokkyo Medical University Koshigaya Hospital Mibu, Shimotsuga, Tochigi Japan

38. Department of Pediatrics, Graduate school of medicine Gifu University Gifu Japan

39. Department of Obstetrics and Gynecology Chuden Hospital Hiroshima Japan

40. Departments of Obstetrics and Gynecology Tokyo University Hospital Tokyo Japan

41. Division of Clinical Genetics Nippon Medical School Hospital Tokyo Japan

42. Department of Clinical Genetics Nagoya City West Medical Center Nagoya Japan

43. Departments of Obstetrics and Gynecology Hyogo Prefectural Amagasaki General Medical Center Amagasaki, Hyogo Japan

44. Departments of Obstetrics and Gynecology Fukuoka University Hospital Fukuoka Japan

45. Departments of Genetic Counseling Ochanomizu University Tokyo Japan

Funder

the National Center for Child Health and Development

Publisher

Wiley

Subject

Obstetrics and Gynecology

Reference39 articles.

1. The Japan Society of Obstetrics and Gynecology. [Policy statement on noninvasive testing of fetal aneuploidy using maternal blood 2013.] [Cited 25 December2016] Available from URL:http://www.jsog.or.jp/news/pdf/guidelineForNIPT_20130309.pdf(in Japanese).

2. Les acides nucleiques du plasma sanguin chez l'homme;Mandel P;C R Seances Soc Biol Fil,1948

3. Free DNA in the serum of cancer patients and the effect of therapy;Leon SA;Cancer Res,1977

4. Isolation and characterization of DNA from the plasma of cancer patients

5. Presence of fetal DNA in maternal plasma and serum

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