Susceptibility of a Herpes Simplex Virus Ribonucleotide Reductase Null Mutant to Deoxyribonucleosides and Antiviral Nucleoside Analogs

Author:

Yamada Yoshinari1,Yamamoto Naohiko1,Daikoku Tohru1,Nishiyama Yukihiro1

Affiliation:

1. Laboratory of Virology, Research Institute for Disease Mechanism and Control; Nagoya University School of Medicine; Nagoya Aichi 466

Publisher

Wiley

Subject

Virology,Immunology,Microbiology

Reference20 articles.

1. Ribonucleotide reductase induced by herpes simplex virus type 1 virus. Characterization of a distinct enzyme;Averett;J. Biol. Chem.,1983

2. Ribonucleotide reductase encoded by herpes simplex virus is a determinant of the pathogenicity of the virus in mice and a valid antiviral target;Cameron;J. Gen. Virol.,1988

3. Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir;Coen;Antimicrob. Agents Chemother.,1989

4. Role of viral ribonucleotide reductase in the increase of dTTP pool size in herpes simplex virus-infected Vero cells;Daikoku;J. Gen. Virol.,1991

5. Mechanism of inhibition of human cytomegalovirus replication by oxetanocin G;Daikoku;Biochem. Biophys. Res. Commun.,1991

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