1. Department of Pharmaceutical Sciences; Tohoku University Hospital; Sendai Miyagi 980 Japan
2. Saikinkagaku Institute Co., Ltd.; Sendai Miyagi 980 Japan
3. Shionogi Institute for Medical Science; Settsu Osaka 599 Japan
4. Department of Surgery; National Sendai Hospital; Sendai Miyagi 980 Japan
5. The Sendai Institute for Microbiology; Sendai Miyagi 980 Japan