The Production of Nitric Oxide and Tumor Necrosis Factor by Murine Macrophages Infected with Mycobacterial Strains Differing by Hemolytic Activity

Author:

Rudnicka Wiesława1,Brzychcy Marzena1,Klink Magdalena2,Lopez Arley Gomez3,Fonteyne Pierre Alain3,Rüsch-Gerdes Sabine4,Rózalska Barbara1

Affiliation:

1. Department of Infectious Biology; Institute of Microbiology and Immunology, University of Łódź; 90-237 Łódź Banacha 12 Poland

2. Department of Immunology; Microbiology and Virology Centre, Polish Academy of Science; 93-232 Łódź Lodowa 106 Poland

3. Department of Microbiology; Institute of Tropical Medicine; Nationale-Straat 155 2000 Antwerp en Belgium

4. National Reference Centre for Mycobacterium Forschungszentrum Borstel; Parkallee 18 23 845 Borstel Germany

Publisher

Wiley

Subject

Virology,Immunology,Microbiology

Reference60 articles.

1. Adams , L.B. Franzblau , S.G. Vavrin , Z. Hibbs , J.B. Krahenbuhl , J.L. 1991 l -Arginine-dependent macrophage effector function inhibit metabolic activity of Mycobacterium leprae J. Immunol. 147 1642 1648

2. Variations in the NRAMPl gene and susceptibility to tuberculosis in West Africans;Bellamy;N. Engl. J. Med.,1998

3. Interleukin-6 antagonizes tumor necrosis factormediated mycobacteriostatic and mycobactericidal activities in macrophages;Bermundez;Infect. Immun.,1992

4. Differential mechanisms of intracellular killing of Mycobacterium avium and Listeria monocytogenes by activated human and murine macrophages: the role of nitric oxide;Bermundez;Cell. Exp. Immunol.,1993

5. Tumor necrosis factor, alone or in combination with IL-2, but not IFN-γ, is associated with macrophage killing of Mycobacterium avium complex;Bermundez;J. Immunol.,1988

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