Acyclovir Resistance in Herpes Simplex Virus Isolates from Keratitis Cases: An Analysis from a Developing Country

Author:

Pramod Naranatt Padmanabhan1,Thyagarajan Sadras Panchatcharam1,Mohan Keta Venkata Krishna1,Anandakannan Kanagasabai2

Affiliation:

1. Department of Microbiology, Dr. ALM Post Graduate Institute of Basic Medical Sciences; University of Madras; Taramani Chennai 600 113 India

2. Cornea Clinic; Regional Institute of Ophthalmology; Egmore Chennai 600 008 India

Publisher

Wiley

Subject

Virology,Immunology,Microbiology

Reference31 articles.

1. Herpesviral deoxythymidine kinases contain a site analogous to the phosphoryl-binding arginine-rich region of porcine adenylate kinase; comparison of secondary-structure predictions and conservation;Balasubramaniam;J. Gen. Virol.,1990

2. Ocular herpes simplex virus infections: reduced sensitivity to acyclovir in primary disease;Charles;Br. J. Ophthalmol.,1990

3. Analysis of the thymidine kinase gene from clinically isolated acyclovir-resistant herpes simplex viruses;Chatis;Virology,1991

4. Comparison of the efficacy and toxicity of acyclovir and of adenine arabinoside when combined with dilute betamethasone in herpetic disciform keratitis: preliminary results of a double-blind trial;Collum;Trans. Ophthalmol. Soc. U.K.,1983

5. Orofacial infection of athymic mice with defined mixtures of acyclovir-susceptible and acyclovir-resistant herpes simplex virus type 1;Ellis;Antimicrob. Agents Chemother.,1989

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