A Limulus Amoebocyte Lysate Activating Activity (LAL Activity) That Lacks Biological Activities of Endotoxin Found in Biological Products

Author:

Ochiai Masaki1,Tamura Hiroshi2,Yamamoto Akihiko1,Aizawa Maki2,Kataoka Michiyo1,Toyoizumi Hiromi1,Horiuchi Yoshinobu1

Affiliation:

1. Department of Safety Research on Biologics; National Institute of Infectious Diseases; Musashimurayama Tokyo 208-0011 Japan

2. Tokyo Research Institute; Seikagaku Corporation; Higashiyamato Tokyo 207-0021 Japan

Publisher

Wiley

Subject

Virology,Immunology,Microbiology

Reference25 articles.

1. Enhancing effect of non-ionic surfactant on the inactivation of lipopolysaccharide by steam-heat treatment I;Bamba;PDA J. Pharm. Sci. Technol.,1996

2. Comparisons of serologic and febrile responses in humans to vaccination with influenza A viruses or their hemagglutinins;Davenport;J. Lab. Clin. Med.,1964

3. European Pharmacopoeia 3rd ed 2000

4. Comparative pyrogenic reactivity of rabbit and man to bacterial endotoxin;Grisman;Proc. Soc. Exp. Biol. Med.,1969

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