Antiviral Effects of 2′,5′ Oligoadenylates (2-5As), and Related Compounds

Author:

Tominaga Akihiro1,Saito Sakura2,Kohno Seiya2,Sakurai Katsukiyo1,Hayakawa Yoshihiro3,Noyori Ryoji4

Affiliation:

1. Tokyo Research Institute; Seikagaku Kogyo Co., Ltd.; Higashiyamato Tokyo 189

2. Department of Measles Virus; National Institute of Health; Musashimurayama Tokyo 190-12

3. Chemical Instrument Center; Nagoya University; Chikusa-ku Nagoya, Aichi 464

4. Department of Chemistry; Nagoya University; Chikusa-ku Nagoya, Aichi 464

Publisher

Wiley

Subject

Virology,Immunology,Microbiology

Reference26 articles.

1. pppA2′p5′A blocks vesicular stomatitis virus in intact cells;Alarcon;J. Virol.,1984

2. Interferon action may be mediated by activation of a nuclease by pppA2′p5′A2′p5′A;Baglioni;Nature,1978

3. A film detection method for tritium labelled proteins and nucleic acids in polyacrylamide gels;Bonner;Eur. J. Biochem.,1974

4. Interferon, double-stranded RNA, and RNA degradation: isolation of homogeneous pppA(2′p5′A)n-1 synthetase from Ehrlich ascites tumor cells;Dougherty;J. Biol. Chem.,1980

5. Dephosphorylated core of 2′-5′ oligoadenylate exerts its antimitogenic effect through mechanism different from the 2′-5′A-dependent endonuclease;Eppstein;J. Interferon Res.,1983

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