Detachment Activity but Not Cytotoxicity Induced in a T-Cell Clone Following Antigen Presentation in the Presence of Thymic Epithelial Cells

Author:

Kaneda Rika1,Kasai Michiyuki2,Itoh Yasushi1,Iwabuchi Kazuya1,Onoé Kazunori1

Affiliation:

1. Section of Pathology, Institute of Immunological Science; Hokkaido University; Sapporo Hokkaido 060 Japan

2. Department of Bacterial and Blood Products; National Institute of Health; shinjuku-ku Tokyo 162 Japan

Publisher

Wiley

Subject

Virology,Immunology,Microbiology

Reference41 articles.

1. Cytotoxic T lymphocyte-induced loss of target cell adhesion and lysis involve common and separate signaling pathways;Abrams;J. Immunol.,1989

2. CD4+ T lymphocyte-induced target cell detachment. A model for T-cell-mediated lytic and nonlytic inflammatory processes;Abrams;J. Immunol.,1991

3. Detachment and lysis of adherent target cells by CD4+ T cell clones involve multiple effector mechanisms;Abrams;Cell. Immunol.,1993

4. Thymic epithelial cells provide unique signals for positive selection of CD4+CD8+ thymocyte in vitro;Anderson;J. Exp. Med.,1994

5. Cytotoxicity of fresh NK1.1+ T cell receptor αβ+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target;Arase;J. Exp. Med.,1994

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