Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug–Drug Interaction and Associated Biomarker Levels in Healthy Volunteers-Reference-Cited by-同舟云学术

Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug–Drug Interaction and Associated Biomarker Levels in Healthy Volunteers

Published:2019-04-13 Issue:4 Volume:12 Page:388-399
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clin Transl Sci

Author:

Yee Sook Wah¹,Giacomini Marilyn M.²,Shen Hong³,Humphreys W. Griffith³,Horng Howard¹,Brian William⁴,Lai Yurong²,Kroetz Deanna L.¹,Giacomini Kathleen M.¹

Affiliation:

1. Department of Bioengineering and Therapeutic SciencesUniversity of California San Francisco California USA

2. Drug Metabolism DepartmentGilead Sciences, Inc. Foster City California USA

3. Department of Metabolism and PharmacokineticsBristol‐Myers Squibb Research and Development Princeton New Jersey USA

4. Disposition Safety and Animal ResearchSanofi‐Aventis Great Valley Pennsylvania USA

Funder

National Institutes of Health

Bristol-Myers Squibb

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12625

Reference39 articles.

1. Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake

2. Organic Anion Transporting Polypeptide (OATP)1B1 and OATP1B3 as Important Regulators of the Pharmacokinetics of Substrate Drugs

3. The Influence of Macrolide Antibiotics on the Uptake of Organic Anions and Drugs Mediated by OATP1B1 and OATP1B3

4. Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells

5. Polymorphisms in OATP-C

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