Predicting Efavirenz Concentrations in the Brain Tissue ofHIV‐Infected Individuals and Exploring their Relationship to Neurocognitive Impairment-Reference-Cited by-同舟云学术

Predicting Efavirenz Concentrations in the Brain Tissue ofHIV‐Infected Individuals and Exploring their Relationship to Neurocognitive Impairment

Published:2019-02-27 Issue:3 Volume:12 Page:302-311
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clin Transl Sci

Author:

Srinivas Nithya¹,Joseph Sarah Beth²,Robertson Kevin²,Kincer Laura P.²,Menezes Prema²,Adamson Lourdes³,Schauer Amanda P.¹,Blake Kimberly H.¹,White Nicole¹,Sykes Craig¹,Luciw Paul³,Eron Joseph J.²,Forrest Alan,Price Richard W.⁴,Spudich Serena⁵,Swanstrom Ronald²,Kashuba Angela D.M.¹²

Affiliation:

1. Eshelman School of PharmacyUniversity of North Carolina at Chapel Hill Chapel Hill North Carolina USA

2. School of MedicineUniversity of North Carolina at Chapel Hill Chapel Hill North Carolina USA

3. School of MedicineUniversity of California Davis California USA

4. Department of NeurologySchool of MedicineUniversity of California San Francisco San Francisco California USA

5. Department of NeurologyYale School of Medicine New Haven Connecticut USA

Funder

National Institute of Allergy and Infectious Diseases

National Institute of Mental Health

National Institutes of Health

National Institute of Neurological Disorders and Stroke

Center for AIDS Research, University of Washington

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12620

Reference40 articles.

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4. Clinical Pharmacokinetics and Pharmacodynamics of Drugs in the Central Nervous System

5. Validation of the CNS Penetration-Effectiveness Rank for Quantifying Antiretroviral Penetration Into the Central Nervous System

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