Use of Titration as a Therapeutic Individualization Strategy: An Analysis of Food and Drug Administration

Use of Titration as a Therapeutic Individualization Strategy: An Analysis of Food and Drug Administration–Approved Drugs

Published:2019-03-12 Issue:3 Volume:12 Page:236-239
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clin Transl Sci

Author:

Schuck Robert N.¹,Pacanowski Michael¹,Kim Sarah²,Madabushi Rajanikanth¹,Zineh Issam¹

Affiliation:

1. Office of Clinical PharmacologyOffice of Translational SciencesCenter for Drug Evaluation and ResearchUS Food and Drug Administration Silver Spring Maryland USA

2. College of PharmacyUniversity of Minnesota Minneapolis Minnesota USA

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12626

Reference5 articles.

1. Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework

2. Scientific and Regulatory Reasons for Delay and Denial of FDA Approval of Initial Applications for New Drugs, 2000-2012

3. Leveraging Genomic Factors to Improve Benefit-Risk

4. Principles of precision medicine and its application in toxicology

5. International Conference on Harmonisation. Efficacy guideline E4: dose‐response information to support drug registration (1994).

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