1. Julius Center for Health Sciences and Primary Care; Utrecht The Netherlands
2. Van Creveldkliniek; University Medical Centre Utrecht; Utrecht The Netherlands
3. Department of Clinical Epidemiology and Biostatistics; McMaster University; Toronto ON Canada
4. Medical Data Solutions and Services Ltd; Manchester UK
5. Department of Cardiovascular Science; University of Sheffield; Sheffield UK
6. Sheffield Haemophilia and Thrombosis Centre; University of Sheffield; Sheffield UK