Parry–Romberg syndrome—Still progressing over 20 years of disease course

Author:

Thoibisana Ashem1,Mishra Biswamohan1ORCID,Elavarasi Arunmozhimaran1ORCID,Singh Rajesh Kumar1ORCID,Vibha Deepti1,Gaikwad Shailesh2,Tripathi Manjari1

Affiliation:

1. Department of Neurology All India Institute of Medical Sciences New Delhi India

2. Department of Neuroradiology All India Institute of Medical Sciences New Delhi India

Abstract

AbstractParry–Romberg syndrome presents with atrophy of one‐half of the face involving skin, soft tissue, muscle, and bone. It usually progresses slowly over 2–20 years and finally stabilizes. Neuropsychiatric abnormalities are subtle, seen in about 10% of the patients, and include cognitive disturbances, aphasia, hallucination, and other psychiatric disorders. We describe the case of a young female who had progressive brain atrophy over 20 years of disease course and presented with focal seizures and recent onset progressive cognitive impairment.

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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