Activation of nucleus accumbens μ‐opioid receptors enhances the response to a glycaemic challenge

Author:

Koekkoek Laura L.123,Kool Tess123,Eggels Leslie123,van der Gun Luna L.123,Lamuadni Khalid123,Slomp Margo123,Diepenbroek Charlene123,Serlie Mireillle J.2,Kalsbeek Andries124,la Fleur Susanne E.123ORCID

Affiliation:

1. Amsterdam University Medical Center, Location AMC Laboratory of Endocrinology Department of Clinical Chemistry Amsterdam Neuroscience Amsterdam Gastroenterology, Endocrinology and Metabolism University of Amsterdam Amsterdam The Netherlands

2. Amsterdam University Medical Center, Location AMC Department of Endocrinology and Metabolism Amsterdam Neuroscience Amsterdam Gastroenterology, Endocrinology and Metabolism University of Amsterdam Amsterdam The Netherlands

3. Metabolism and Reward Group An Institute of the Royal Netherlands Academy of Arts and Sciences Netherlands Institute for Neuroscience Amsterdam The Netherlands

4. Hypothalamic Integration Mechanisms An Institute of the Royal Netherlands Academy of Arts and Sciences Netherlands Institute for Neuroscience Amsterdam The Netherlands

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Endocrine and Autonomic Systems,Endocrinology,Endocrinology, Diabetes and Metabolism

Reference50 articles.

1. Effects of morphine on glucose homeostasis in the conscious dog.

2. Morphine‐induced hyperglycemia in the cat;Borison HL;J Pharmacol Exp Ther,1962

3. Differential effects of subcutaneous and intrathecal morphine administration on blood glucose in mice: comparison with intracerebroventricular administration;Lux F;J Pharmacol Exp Ther,1988

4. Beta-endorphin inhibits glucose production in the conscious dog.

5. Beta-endorphin-induced inhibition and stimulation of insulin secretion in normal humans is glucose dependent

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1. Endogenous opiates and behavior: 2021;Peptides;2023-06

2. Different brain responses to fat and/or sugar;Medicom Conference Report ECNP 2022;2022-11-28

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