Rationale for the selective administration of tranexamic acid to inhibit fibrinolysis in the severely injured patient
Author:
Affiliation:
1. Denver Health Medical Center; Bonfils Blood Center, Denver Colorado
2. Department of Surgery; University of Colorado; Denver Colorado
3. Department of Research; Bonfils Blood Center; Denver Colorado
Publisher
Wiley
Subject
Hematology,Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/trf.13486/fullpdf
Reference45 articles.
1. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial;Roberts;Lancet,2011
2. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial;Shakur;Lancet,2010
3. Tranexamic acid in trauma: how should we use it?;Napolitano;J Trauma Acute Care Surg,2013
4. Tranexamic acid and trauma: current status and knowledge gaps with recommended research priorities;Pusateri;Shock,2013
5. Fibrinolysis: its mechanism and significance;Macfarlane;Blood,1948
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