Effect of hyperglycaemia on muscarinic M3 receptor expression and secretory sensitivity to cholinergic receptor activation in islets
Author:
Affiliation:
1. Diabetes Research Group, Division of Diabetes and Nutritional Sciences; King's College London; London UK
2. Universidad Nacional Autónoma de México, Facultad de Estudios Superiores Iztacala; UBIMED; Tlalnepantla de Baz Mexico
Funder
Diabetes UK
National Centre for the Replacement, Refinement and Reduction of Animals in Research
Medical Research Council
Publisher
Wiley
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/dom.12301/fullpdf
Reference48 articles.
1. Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function;Gilon;Endocr Rev,2001
2. A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo;Gautam;Cell Metab,2006
3. Quantitative and functional characterization of muscarinic receptor subtypes in insulin-secreting cell lines and rat pancreatic islets;Iismaa;Diabetes,2000
4. Increased insulin secretion by muscarinic M1 and M3 receptor function from rat pancreatic islets in vitro;Renuka;Neurochem Res,2006
5. Effects of muscarinic receptor type 3 knockout on mouse islet secretory responses;Zawalich;Biochem Biophys Res Commun,2004
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