Development and preclinical evaluation of a vaccine targeting IL‐4 and IL‐13 for the treatment of allergic asthma

Author:

Conde Eva12,Bruhns Pierre1,Serra Vincent2,Reber Laurent L.3ORCID

Affiliation:

1. Institut Pasteur Unit of Antibodies in Therapy and Pathology UMR 1222 INSERM Paris France

2. Neovacs SA Paris France

3. Toulouse Institute for Infectious and Inflammatory Diseases (Infinity) INSERM UMR1291CNRS UMR5051University Toulouse III Toulouse France

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference10 articles.

1. Type 2 inflammation in asthma — present in most, absent in many

2. Targeting cytokines to treat asthma and chronic obstructive pulmonary disease

3. Grouard‐VogelG Conde GarciaE BertrandR et al.WO2019228674A3: Immunogenic product comprising il‐4 and/or il‐13 for treating disorders associated with aberrant il‐4 and/or il‐13 expression or activity;2020.

4. Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197

5. Control of allergic reactions in mice by an active anti-murine IL-4 immunization

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