Abstract
The relationship between olanzapine metabolism by CYP1A2/CYP2D6 and hyperglycaemia was investigated. The higher blood olanzapine concentration may be effected by the abnormal metabolism, but not always caused by hyperglycaemia.
Publisher
Cambridge University Press (CUP)
Subject
Biological Psychiatry,Psychiatry and Mental health
Reference7 articles.
1. New antipsychotic agents for schizophrenia: pharmacokinetics and metabolism update;Caccia;Curr Opin Invest Drugs,2002
2. Manifestation eines Diabetes mellitus unter Therapie mit Olanzapin
3. Detection of Three Genetic Polymorphisms in the 5′-Flanking Region and Intron 1 of Human CYP1A2 in the Japanese Population
4. Fatality from Olanzapine Induced Hyperglycemia
5. Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism;Gaedigk;Am J Hum Genet,1991
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献