Phosphatidylinositol (4, 5)-bisphosphate targets double C2 domain protein B to the plasma membrane

Author:

Michaeli Lirin1,Gottfried Irit1,Bykhovskaia Maria2,Ashery Uri13

Affiliation:

1. Department of Neurobiology, Faculty of Life Sciences; Tel-Aviv University; Tel Aviv Israel

2. Department of Neurology; Wayne State University; Detroit Michigan

3. Sagol School of Neuroscience; Tel-Aviv University; Tel Aviv Israel

Funder

Israel Science Foundation

National Institutes of Health

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology

Reference71 articles.

1. Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release;Groffen;Science (New York, NY),2010

2. DOC2B and Munc13-1 differentially regulate neuronal network activity;Lavi;Cereb. Cortex (New York, NY: 1991),2014

3. Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release;Yao;Cell,2011

4. DOC2B acts as a calcium switch and enhances vesicle fusion;Friedrich;J Neurosci,2008

5. Mutations that disrupt Ca2+-binding activity endow Doc2ß with novel functional properties during synaptic transmission;Gaffaney;Mol Biol Cell,2014

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