Beating the odds: efficacy and toxicity of dihydropyrimidine dehydrogenase-driven adaptive dosing of 5-FU in patients with digestive cancer-Reference-Cited by-同舟云学术

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Beating the odds: efficacy and toxicity of dihydropyrimidine dehydrogenase-driven adaptive dosing of 5-FU in patients with digestive cancer

Published:2015-11-28 Issue:1 Volume:81 Page:124-130
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Launay Manon¹,Dahan Laetitia²,Duval Manon¹,Rodallec Anne¹,Milano Gérard³,Duluc Muriel²,Lacarelle Bruno¹⁴,Ciccolini Joseph¹⁴,Seitz Jean-Francois²

Affiliation:

1. Laboratoire de Pharmacocinétique La Timone University Hospital of Marseille; Marseille

2. Digestive Oncology Unit; La Timone University Hospital of Marseille; Marseille

3. Oncopharmacology Unit; Centre Antoine Lacassagne; Nice

4. SMARTc Unit; U911 Cro2 Aix-Marseille Univ.; Marseille France

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12790/fullpdf

Reference30 articles.

1. The current landscape of locally advanced rectal cancer;Aklilu;Nat Rev Clin Oncol,2011

2. Routine dihydropyrimidine dehydrogenase testing for anticipating 5-fluorouracil-related severe toxicities: hype or hope?;Ciccolini;Clin Colorectal Cancer,2010

3. Severe toxicity related to the 5-fluorouracil/leucovorin combination (the mayo clinic regimen): a prospective study in colorectal cancer patients;Tsalic;Am J Clin Oncol,2003

4. Population study of dihydropyrimidine dehydrogenase in cancer patients;Etienne;J Clin Oncol,1994

5. Profiling dihydropyrimidine dehydrogenase deficiency in patients with cancer undergoing 5-fluorouracil/capecitabine therapy;Mercier;Clin Colorectal Cancer,2006

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