Affiliation:
1. Institute of Pharmacology, National Yang Ming Medical College, Shih-Pai, Taipei, Taiwan, Republic of China
Abstract
Abstract
Comparisons of chronotropic effects of sympathomimetic and parasympathomimetic agents were made in isolated atria from alloxan-induced diabetic and age-matched control mice. In atria from mice rendered diabetic for three months, the cardiac response to bethanechol was potentiated compared with that of the age-matched control atria. However, the cardiac responses of atria from alloxan-treated mice to noradrenaline, 3-isobutyl-1-methylxanthine and 1,1-dimethyl-4-phenyl piperazinium iodide were similar to those of the controls.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
4 articles.
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