The evaluation of a molecular sieve technique to determine the interaction between a preservative and a surfactant-Reference-Cited by-同舟云学术

The evaluation of a molecular sieve technique to determine the interaction between a preservative and a surfactant

Published:1966-12 Issue:Supplement_1 Volume:18 Page:98S-102S
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

ASHWORTH R W¹,HEARD D D¹

Affiliation:

1. Pharmaceutical Department, Imperial Chemical Industries Limited, Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire, England

Abstract

Abstract The interaction between methyl p-hydroxybenzoate and polysorbate 80 has been determined using a molecular sieve technique. At 25° and at surfactant concentrations of 2·86 and 1·43% respectively, the ratios of total to free preservative were 2·9 and 1·9. These results are comparable with published data.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/18/Supplement_1/98S/37681907/j.2042-7158.1966.tb07969.x.pdf

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1. Drug-Plasma Binding Measured by Sephadex

2. Interaction of Parabens with Nonionic Macromolecules

3. Studies on gel filtration

4. The interaction of benzoic acid and chloroxylenol with cetomacrogol

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