Simultaneous polarographic determination of 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole, 1-(2-hydroxyethyl)-2-methyl-4-nitroimidazole and 2-methyl-5-nitroimidazole

Author:

DUMANOVIĆ D1,VOLKE J2,VAJGAND V3

Affiliation:

1. Razvojna laboratorija “Galenika”, Zemun, Yugoslavia

2. J. Heyrovský Institute of Polarography, Czechoslovak Academy of Sciences, Prague, Czechoslovakia

3. Faculty of Science, The University, Belgrade, Yugoslavia

Abstract

Abstract A method for the simultaneous quantitative polarographic determination of the three components in reaction mixtures has been proposed. The analysis is based on a separation of the half-wave potentials in strongly alkaline base solutions. The general polarographic behaviour of the three substances is also described.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

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