Affiliation:
1. Pharmacy Department, University of Sydney, Australia
Abstract
Abstract
The rates of hydrolysis of chlorbutol are reduced by surface-active agents, but not by polyethylene glycols. The ratio of the rate-constant in simple aqueous systems to that in systems containing surface-active agents can be predicted if the distribution coefficient for chlorbutol between the micellar pseudo-phase and the aqueous phase is known and is independent of concentration.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
11 articles.
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