The polarographic determination of chlorpromazine and chlorpromazine sulphoxide-Reference-Cited by-同舟云学术

The polarographic determination of chlorpromazine and chlorpromazine sulphoxide

Published:1966-04 Issue:4 Volume:18 Page:223-227
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

PORTER G S¹,BERESFORD JEAN¹

Affiliation:

1. Pharmaceutical Chemistry Laboratories, Department of Pharmacy, Liverpool Regional College of Technology, New Building, Byrom Street, Liverpool

Abstract

Abstract Cathodic polarography of solutions containing between 0·1 and 5·0 μg/ml of both chlorpromazine and its sulphoxide enables the sulphoxide to be determined directly. Reductive polarography of the solution after bromination gives an additive wave from which the chlorpromazine is determined by subtraction. The method has been applied to urine, interfering substances being removed by ion-exchange on Amberlite resins.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/18/4/223/37680686/j.2042-7158.1966.tb07855.x.pdf

Reference4 articles.

1. Relative Instability of Chlorpromazine in N Alkali

2. Spectrophotometric Method for the Determination of Chlorpromazine and Chlorpromazine Sulphoxide in Biological Fluids

3. A COMPREHENSIVE METHOD FOR THE DETERMINATION OF URINARY CHLORPROMAZINE AND ITS OXIDATIVE METABOLITES

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3. Flow injection analysis of three N-substituted phenothiazine drugs with amperometric detection at a carbon fibre array electrode;The Analyst;1985

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