Affiliation:
1. Centre régional de Transfusion Sanguine et d'Hématologie, 54511 Vandoeuvre les Nancy Cédex and Faculté des Sciences pharmaceutique et biologique, 54001 Nancy Cédex, France
Abstract
Abstract
The effects in-vitro of two non-steroidal anti-inflammatory drugs, diclofenac and indomethacin, have been studied on human polymorphonuclear functions. Adhesivity and chemotaxis were decreased by the two drugs, but in a manner that varied with the attractant used. As shown by the nitro blue tetrazolium slide test, all cells remained active but the production of oxygen metabolites by opsonized zymosan was decreased in the presence of diclofenac.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
6 articles.
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